Ro18-5362
产品描述
Ro18-5362 is the less active prodrug of Ro 18-5364.
体外活性 Marked differences are seen between Ro 18-5364 (sulfoxide) and Ro18-5362 (sulfide) with regard to inhibitory activity[1]. The sulfoxide Ro 18-5364 is a potential metabolite of the IND Ro18-5362,and is a powerful inhibitor of gastric mucosal (H++K+)-ATPase, decreasing enzymatic activity with an apparent Ki of 0.1 μM[2].
分子量 395.52
分子式 C22H25N3O2S
CAS No. 101387-97-7
存储
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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